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IBS (Irritable Bowel Syndrome) is a chronic disorder of gut-brain interaction, defined by abdominal pain and altered bowel habits without any visible structural disease

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nor state which other risk factors were associated with development of DME

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Melanotan 1 (MT1) and Melanotan 2 (MT2) are synthetic peptides derived from alpha-melanocyte-stimulating hormone (a-MSH), and they serve a range of physiological and therapeutic applications