tirzepatide surpass-5 Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial Post Hoc Analysis of SURPASS-1

It includes everything in the Silver tier, plus essential vitamins and minerals that support thyroid function: Vitamin D, B12, and Folate: Deficiencies in these can mimic or worsen thyroid symptoms

additional contraceptive methods are advised for 4 weeks after starting treatment and after each dose increase Patients with severe gastrointestinal disease (e.g., gastroparesis) should generally avoid Mounjaro If the patient is on insulin, doses should not be rapidly reduced when starting Mounjaro, as this increases the risk of diabetic ketoacidosis Patients should be counselled to report symptoms suggestive of thyroid C-cell tumours (neck mass, difficulty swallowing, persistent hoarseness) A collaborative approach involving endocrinologists, GPs, and diabetes specialists is often beneficial to ensure comprehensive care and monitoring

The cost of these medications can vary depending on dosage, insurance coverage, and other factors

doi:10.1172/JCI75276 55

Criteria Pressure relief: Each mattress tester, including myself, lay on our side, back and stomach for several minutes each, and then recorded whether or not we felt pressure accumulation in specific areas like the hips and shoulders

Its also a very small study