Cell 149, 10601072
Without knowing the dose, you cannot compare it to the doses used in actual research
If the molecular chaperone functions of HSP70 and HSP90 are impaired by genetic deletion, mutation, or pharmacological inhibition, cells may become less efficient at recognizing, refolding, or clearing misfolded proteins, thereby compromising proteostasis recovery (Rutledge et al., 2022
Dermal Model Utility: Used in skin-related research that evaluates matrix organization and tissue structure markers
Burke O, Sa B, Cespedes DA, Tosti A
Rats showed slightly better performance compared to mice, with the C_max and AUC of IV and PO administration showing a doubling in growth, yet the bioavailability was only around 20%