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Unless stabilized and formulated to overcome these obstacles, orally delivered peptides suffer from poor bioavailability and short half-lives, which may limit efficacy even with frequent dosing
Characterizing the mechanism of action for mRNA therapeutics for the treatment of propionic acidemia, methylmalonic acidemia, and phenylketonuria
4 Hydroxocobalamin : A form of vitamin B 12 used in injectable medications, often used to treat vitamin B 12 deficiency
During this process, acetyl-CoA produced by the pyruvate dehydrogenase (PDC) complex in muscle exceeds the processing capacity of the tricarboxylic acid (TCA) cycle
Webb C, Bedwell C, Guth A, Avery P, Dow S
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