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N., & Blumberg, J
Potentially severe side effects of Trulicity: Hypoglycemia Gastroparesis (stomach paralysis) Ileus (intestinal blockage) Gallbladder disease Kidney damage Pancreatitis Thyroid tumors (Trulicity carries a boxed warning of thyroid tumors after studies showed an increased risk in animals, but had unclear implications for humans) Allergic reactions Signs and symptoms of serious side effects may include severe abdominal pain, persistent nausea, vomiting, fever, dark urine, or signs of an allergic reaction
References 1 AggarwalS.MannamP.ZhangJ
Where can I find more information on peptide therapies
Although previous studies showed a lack of therapeutic benefit for GIP agonists, current studies show that the glucose lowering and weight loss effects of tirzepatide are at least as effective as GLP-1 RAs with a similar adverse effect profile
This delayed gastric emptying contributes to reduced postprandial glucose excursions and increased feelings of fullness, though this effect may diminish over time with continued use
