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Due to this high aerobic demand, the generation of high amounts of ROS and other oxidative by-products is unavoidable (Halliwell, 2006)
The clearest way to know is through diagnostic tests
doi:10.1128/AAC.01446-21 68
Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra-virgin olive oil or nuts
Significant enhancement of the brain distribution of DOX-loaded liposomes as well as higher anti-tumor efficacy were found
Specifically, autophagy suppresses anoikis induced by the detachment of cancer cells from the extracellular matrix (ECM) and hence promotes metastasis 169
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