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As we age, our bodies produce less collagen, which leads to wrinkles, sagging skin, and other signs of aging

Hypertension is a strong risk factor for age-related dementia that is characterized by both beta amyloid (A) deposition and vascular dysfunction 3

These processes not only compromise cellular bioenergetics but also trigger immune responses through sensors such as cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING), or activate NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasomes, leading to secretion of proinflammatory cytokines such as interleukin (IL)-1 (Mills et al., 2017)

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