b12 ampoule injection 5000mcg Hydroxocobalamin Ampoules B12 Shots at Home: How,

Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)

Last reviewed: May 12, 2026 Last updated: May 12, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

The injection site is usually the upper arm or thigh

Vitamin B12 has a very low risk of toxicity, so there's really no upper limit to how much you can take without harm

Technique for Maximum Absorption To get the most out of the shots, the right technique is important

The effect on truly "stubborn" subcutaneous fat (which is resistant due to higher alpha-2 adrenergic receptor density) is unclear