2011 Jan;60(1):79-86
OSullivan RJ, Arnoult N, Lackner DH, Oganesian L, Haggblom C, Corpet A, Almouzni G, Karlseder J (2014) Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1
R.NemotoT.MiyashitaY.IinoM.KasaiH
The proline substitutions at positions 25, 28, and 29 were specifically engineered to suppress the beta-sheet aggregation pathway that destabilises native human amylin in aqueous solution
The 5mg format provides researchers with a practical quantity of material suitable for multiple laboratory applications while supporting accurate measurement, handling, and experimental consistency
This depletion compromises the brains antioxidant defense, leading to increased oxidative damage and neuronal death