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its blockade increases serotonin release Promotes neurogenesis : TREK-1 knockout mice show increased hippocampal neurogenesis, and PE-22-28 recapitulates this effect pharmacologically within 4 days of treatment Induces synaptogenesis : TREK-1 blockade promotes dendritic growth and synaptic connection formation PE-22-28 inhibits TREK-1 with an IC50 of 0.12 nM, making it approximately 300-500 times more potent than spadin
In this context, the searcher is a qualified researcher, laboratory buyer, research institution, or technical procurement team evaluating whether a research-use-only peptide blend is properly labeled, documented, and traceable
The compounds discussed are for laboratory research use only and are not intended for human consumption
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Food and Drug Administration) and are not intended to diagnose, cure, treat, mitigate, or prevent any medical condition or disease
