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ME/CFS specialists generally recommend comparatively lower doses than standard followed by gradual titration, colloquially referred to as the start low, go slow strategy

Call your healthcare provider right away if you have any mental changes that are new, worse, or worry you

In a clinical trial, the GLP-1 analogue liraglutide added to metformin significantly lowered HbA1c in comparison with metformin alone 47

PMC Cognitive Function and Neurological Research Robillard JM, et al

JAMA 2025, 333, 113114

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