l-carnitine function fatty acid transport mitochondria Nutritional and Hormonal Regulation of Citrate and Carnitine/Acylcarnitine Transporters: Two Mitochondrial Carriers Involved in Metabolism Role of Carnitine Shuttle System

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The 4-substituted benzyl chain formed a hydrophobic bond with F424 and F427, while the C3-(4-fluorophenyl) amino side chain occupied a lipophilic pocket made up of F392, L409, and V417 (Figures 7A,B)

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Tirzepatide is a dual glp-1/gip receptor agonist FDA-approved for weight loss and type 2 diabetes

doi:10.1007/s00384-014-2030-8