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GLP-1 receptor agonists, with their proven track record for helping patients lose weight and regulate blood sugar, are now a seemingly permanent part of the weight loss landscape

Even the approved 4g/day dose for two weeks can raise liver enzyme levels in about a third of patients

Unlike GLP-1 receptor agonists, DPP-4 inhibitors typically have a more modest effect on HbA1c reduction (usually 0.50.8% decrease or approximately 59 mmol/mol) and are generally weight-neutral

In addition, GLP-1RA preserves gut microbiota and prevents intestinal dysbiosis (Megur et al

Transdermal hormone therapy and the risk of stroke and venous thrombosis

Tarantini, G., Scrutinio, D., Bruzzi, P., Boni, L., Rizzon, P., and Iliceto, S