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Ipamorelin is a selective GH secretagogue that triggers pituitary GH release without raising cortisol or prolactin (Raun et al., Eur J Endocrinol, 1998)
Preclinical investigations indicate that the peptide may attenuate behavioral and functional disturbances in rodent models of neurodegeneration induced by neurotoxic agents such as MPTP and reserpine
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Specifically, BV2 and HT22 cells were incubated in 24well plates (1 10 5 cells/well) for 24 h
Smith SR, Weissman NJ, Anderson CM, Sanchez M, Chuang E, Stubbe S, et al
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