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Although some clues suggest the possibility of lipid domains in nuclear (Ramamurthy et al., 2018) and mitochondrial membranes ( FIGURE 1 Lipid Domains of the Endoplasmic Reticulum The ER is the largest cellular membrane system, consisting of a contiguous network of membrane tubes and sheets that comprises the cells center for lipid metabolism (Shibata et al., 2006)

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