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Springer Newsome PN, et al
UK standard treatment regimens (per BNF and NHS guidance): Dietary deficiency (e.g., in vegans): oral cyanocobalamin 50150 micrograms daily between meals Pernicious anaemia or other absorption-related deficiency : intramuscular hydroxocobalamin 1 mg on alternate days for two weeks (loading), then 1 mg every two to three months as maintenance
- review the frequency of the intervention if B12 levels are near or above the acceptable range
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EDS Clinical Presentations Image source: Malfait et al., 2020 Management of Ehlers-Danlos Syndrome The treatment of EDS usually involves a multidisciplinary approach
The peptides may have potential roles as adjunctive therapies or alternative treatments for patients who cannot tolerate or do not respond adequately to conventional treatments, but this should be based on careful risk-benefit analysis and appropriate patient selection
