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140 Correspondingly, H3K9 exhibits remarkable hyperlactylation in VEGF-induced ECs and oxygen-induced retinopathy mouse retinas, leading to increased expression of angiogenic genes, including NECTIN1, TGFBR2, ABL1, PTGFR, LAMA4, CLASP2, PRCP, and EGFR

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They are signaling molecules that instruct other molecules and cells on the functions they should perform

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Understanding this mechanism helps explain the impressive blood sugar results observed in clinical research

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