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It is also worth seeking advice if you follow a vegan or vegetarian diet, take medications that may affect B12 absorption, or have a digestive condition that may increase your risk of deficiency
However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)
Retinol activates nuclear retinoic acid receptors and drives collagen gene transcription, but frequently causes irritation, peeling, and photosensitivity at therapeutic concentrations
Total gastrectomy always produces vitamin B12 deficiency
It looks like increased breakouts but is actually a sign the medication is working
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