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Currently, platinum-based chemotherapy in OC treatment increases intracellular ROS levels, leading to damage to macromolecules such as nucleic acids and proteins, ultimately resulting in cell death
Supplementation with 3.3 mg of spermidine via grain roll with wheat germ or introducing spermidine-rich food with at least 3.3 mg of spermidine per daily intake can promote cognitive performance, especially in people with mild dementia 128,129
27 One animal study suggested that severe glutathione deficiency during early development may reduce BDNF (a brain growth factor) in key brain areas, and potentially be linked to schizophrenia-like behavior
It can also occur on the forehead, chin, and cheeks
Konstantinopoulos PA, Cheng S-C, Wahner Hendrickson AE, Penson RT, Schumer ST, Doyle LA, et al
Hepatology 48 , 19982006 (2008)
