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This biphasic response curve, where both microgram and nanogram doses work equally well, is unusual and mechanistically unclear
Runx2/Osterix pathway: Upregulation of Runx2 (osteogenic differentiation core transcription factor) and Osterix expression induces directed differentiation of bone marrow mesenchymal stem cells into osteoblasts and increases new bone formation
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It was developed in Russia, where it holds pharmaceutical approval for the treatment of stroke and cognitive disorders
