Gastrointestinal adverse events - predominantly nausea, vomiting, diarrhea, and constipation - are the most common class effects, occurring in 20%-60% of patients depending on the agent and dose, and are typically of mild-to-moderate severity, dose-dependent, and most prominent during titration
Research indicates that exogenous PYY can inhibit the proliferation and metastasis of colorectal cancer cells, enhancing cancer cells apoptosis [19]
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GLP-1 receptor agonists work by mimicking a natural hormone that helps regulate blood sugar, control appetite, and support weight loss
Proton pump inhibitors are often ineffective for treating such cough
GLP-1 receptor agonists like tirzepatide can reduce B12 absorption over time by slowing gastric motility