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Ancestral resurrection and directed evolution of fungal mesozoic laccases
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M., Despotovic, A
Antigen-specific tolerance This strategy aims to retrain the immune system to recognize islet antigens as self. Approaches include vaccines (e.g., with GAD65) or nanoparticles designed to deliver self-antigens in a tolerogenic context to antigen-presenting cells, potentially inducing antigen-specific Tregs or anergy in autoreactive T cells [122]
Modulation of expression of LOXs family members through transcriptional regulation of HIF-1 may become promising therapeutic approaches for treating aging-induced cartilage degeneration as potential rejuvenating therapies
Neither method is automatically best for every patient
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