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Studies have shown (see full study below) health benefits with as little as 5% reduction of total body weight

Jaubert MP, Jin Z, Russo C, Schwartz JE, Homma S, Elkind MS, et al

doi: 10.1002/sim.1186 9 HigginsJPGreenS

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The medication acts as a triple hormone receptor agonist at glucagon-like peptide-1 receptors, glucose-dependent insulinotropic polypeptide receptors, and glucagon receptors