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Apart from the pancreas, GLP-1R is also widely distributed in various tissues of the body including the lungs, kidneys, central nervous system, cardiovascular system, gastrointestinal tract, and skin and vagus nerves (17)

Moreover, clinical trials evaluating PDE1 and PDE10A inhibitors have yielded inconsistent outcomes, with some compounds demonstrating improvements in cognitive or negative symptoms, while others failed to achieve primary endpoints

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Purification, regulation and cloning of a glutathione transferase (GST) from maize resembling the auxin-inducible type-III GSTs

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