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Initially considered the sole enzyme capable of degrading GSH, GGT hydrolyzes the -glutamyl bond of extracellular reduced and oxidized GSH (22)

2007 Jul;164(7):1115-7

Another peptide, GHK-Cu, is being studied for potential cosmetic benefits such as for photoaging and hair loss and was added to the Category 1 list (but not for injectable routes of administration)

A family history of vitiligo increases the likelihood of developing the condition

Developing selective NOX inhibitors has been quite challenging due to the high degree of similarity in the core catalytic domains of these enzymes, which makes it difficult to achieve selectivity for specific isoforms

Erd F, Bors LA, Farkas D, Bajza , Gizurarson S