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[16] Lauritano E, Bilotta A, Gabrielli M et al
Of these 50 semaglutide-treated patients that developed anti-semaglutide antibodies, 28 patients (1.6% of the overall population) developed antibodies cross-reacting with native GLP-1.The in vitro neutralizing activity of the antibodies is uncertain at this time
Tirzepatide, better known as Zepbound for weight loss and Mounjaro for treatment of type 2 diabetes, helped patients lose more than 20% of their starting body weight across the reviewed studies
Claims that either compound is "safe for human use" are not supported by adequate clinical evidence
B12 shots are widely considered safe, but a few situations may require extra care