Note: Tirzepatide is technically a dual agonist (GLP-1 + GIP), meaning it targets two hormone receptors for potentially stronger effects
Weight regain can occur, which is why long-term habits, muscle preservation, and a maintenance plan are important
You may want to consider a comprehensive approach to liver health
Here are the most common ones and what to do instead
Although the shown enhancement of POMC neuronal activity is likely to contribute to the observed increased weight loss with GLP-1GIPLani relative to GLP-1GIP, mechanisms in the hindbrain are also known to account for GLP-1-induced weight loss, and may thus also have a role in the increased weight loss induced by GLP-1GIPLani relative to GLP-1GIP
When GLP-1 binds to these brain receptors, it triggers signalling cascades that affect neuronal activity and cellular survival