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While uncommon, nausea, vomiting, and diarrhea are frequently observed as side effects of semaglutide, typically diminishing after a few weeks of medication use
Clinical trials show 14.9% average body weight reduction with semaglutide versus modest scale changes with sermorelin
Kumar S, Trivedi PK
ncbi.nlm.nih.gov/books/NBK436016/ #2
This concern appears in the prescribing information for Egrifta and represents a known risk of any intervention that elevates growth hormone or IGF-1
Whether it ultimately becomes a major player alongside Retatrutide remains to be seen, but one thing is clear: The era of multi-agonist metabolic peptides and triple-hormone incretin science is just getting started
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