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Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

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Co-treatment with Spirulina platensis aqueous extract (SPAE) led to a dose-dependent reduction in Keap1 expression, with the 800 mg/kg dose showing the most pronounced effect (0.80 0.05), significantly lower than both the DEX and SPAE 400 mg/kg groups (1.20 0.07)