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Vineyard Health prescribes the GLP-1 receptor agonists discussed in this article, and is the practice from which the Tinsley & Nadolsky 2025 case series was drawn

Moreover, Glp1r Tie2/ mice do not display differences in renal artery or kidney Glp1r expression, as opposed to Glp1r VSM/ mice in which Glp1r expression is markedly reduced in these structures, further highlighting that VSMCs are the main renal GLP-1Rexpressing cell type

T.Perez-TilveD.WardB.et al

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Below we investigate the model further to better isolate the essential component of the dynamics responsible for this feature