Pay in 4 interest-free payments of $5.05 Learn more
Ships within 48 hours · Estimated delivery Aug 19 - Aug 24
Maintenance and Long-Term Use: STEP-4 Trial: Participants who stopped semaglutide regained most weight Those who continued maintained loss and continued losing Suggests long-term treatment necessary for maintenance Most experts recommend: Treating obesity as chronic disease Long-term or indefinite medication use Transitioning to maintenance dose (not stopping) Combining with lifestyle changes for best results Understanding the complete comparison between semaglutide and tirzepatide helps determine which medication best fits your goals
It binds to the glucagon-like peptide 1 (GLP-1) hormone and potentiates the synthesis and secretion of insulin from pancreatic -cells in a glucose-induced manner (Underwood et al., 2009)
In terms of weight reduction outcomes, tirzepatide (22.5% at 72 weeks) sits between semaglutide (16% at 68 weeks) and retatrutide (24.2% at 48 weeks)
Stephen Sinatra
Some protocols might also use intramuscular injections (into muscle), though subcutaneous is more common due to better tolerability
PIONEER 3 Investigators
US$ 24.66
US$ 23.26
US$ 20.79
US$ 28.94
US$ 20.49
