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More specifically, the number and density of CD8+ T cells in close proximity to pancreatic islets are elevated in AAb+ and T1D patients and, as the disease progresses, further accumulation is observed (30, 34)
These GI side effects typically peak during the first 4-8 weeks and improve as your body adjusts to the medication
You may experience fatigue or lethargy, among other symptoms, if you have a B12 deficiency
It usually resolves within the first week after a dose increase
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