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In neurons, Grx has a protective effect on redox-sensitive enzymes and ion channels, meaning that its dysfunction is implicated in several neurodegenerative disorders involving protein misfolding and redox signaling dysregulation (Ogata et al., 2021)

doi: 10.1186/s12864-017-4195-3 48 GuoD.ParkC.LiY.LiB.YangQ.DengY.et al

BPC-157 has been shown to promote angiogenesis (new blood vessel formation)

While this typically means morning administration for many patients, the critical factor is taking it before the first intake of the day, which may be at different times for shift workers

Trials with head-to-head comparison would be necessary to demonstrate possible superiority of a drug within the GLP-1RA class

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