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It uses a methyl group donated by S-adenosylmethionine (SAM) to methylate nicotinamide a vitamin B3 form that would otherwise be recycled back into NAD+

Unexplained hypercobalaminemia, particularly levels above 1,000 pg/mL, has been associated with liver disease, kidney dysfunction, myeloproliferative disorders, and certain solid cancers in multiple large-scale studies

Relative risk and absolute risk look very different

Table of Contents: What is Vitamin B12, and what does it do in the body

The information in this article is for educational purposes

Daily doses are necessary, yet we have many readers who complain of only being able to obtain an injection every few weeks or months