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As a proxy for heavy smoking (binary variable), we used diagnosis codes related to lung diseases highly associated with tobacco exposure along with diagnosis codes related to nicotine or tobacco, previous use of medications for the treatment of tobacco dependence, and initiation of drugs for obstructive airway disease after the age of 40
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Main Indications : memory and concentration support, cognitive function in seniors, mental fatigue, neuroprotection
Diabetes is a progressive condition, and discontinuing effective glucose-lowering therapy typically results in deterioration of glycemic control
Simultaneously, it suppresses PINK1/Parkin-mediated mitophagy, maintaining membrane potential and OXPHOS efficiency while counteracting oxidative stress [235]
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