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Consistent with these observations, animal models with iHSP72 overexpression exhibit improved insulin sensitivity and reduced systemic inflammation, reinforcing its therapeutic relevance

330 For example, CCR2 inhibitors can prevent monocyte-derived TAM accumulation, enhancing the ICB response

doi: 10.1002/ptr.6939 373 ModyDAthamnehAIMSeleemMN

Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis

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