J leukocyte Biol
Through its deacetylase activity, the NAD + -dependent deacetylase sirtuin-1 (SIRT1) meticulously regulates a variety of substrates, such as histone and non-histone proteins, thereby producing significant effects on metabolic homeostasis, apoptosis regulation, inflammatory responses, attenuation of oxidative stress, and even the aging process (Tanno et al., 2007
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a , Schematic diagram of dystrophin and dystrobrevin
10.1038/sj.tpj.6500351 Pharmacogenomics J
After transfection, cells were incubated with fresh medium containing puromycin (1 g/ml) for 3 weeks