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Bhasikuttan, Associate Director, Chemistry Group for the support and encouragement for writing this review article
This remains an area of active investigation rather than settled science
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This extended duration of action is a result of structural modifications made to the GLP-1 molecule, including the addition of a fatty acid chain that allows it to bind more strongly to albumin in the blood, protecting it from enzymatic degradation and reducing renal clearance
Gutgesell A, Wen G, Knig B, Koch A, Spielmann J, Stangl GI, et al
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