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The Increlex label cites preclinical 2-year rat carcinogenicity studies in which increased mammary and skin tumor incidence occurred at high IGF-1 exposure
V.LisovyiO
Int J Pharm Sci Rev Res
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The spontaneous equilibration of protein thiols with the GSH/GSSG couple would be both too slow and too unspecific and, thus, not practical in signaling events
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