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doi: [Research Gate] 48
The rectal route puts KPV directly at the site of distal colonic inflammation, which aligns with the PepT1 uptake data
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As a result, it has a relatively low incidence of producing drowsiness compared to clonidine (Chien et al, 1990
5, 196 (2014) , P
This approach maintains consistent peptide signaling and metabolic effects throughout the treatment period
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