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In vitro studies have demonstrated that butyrate functions as a histone deacetylase (HDAC) inhibitor and an immunosuppressive agent

HPPD is a Fe (II)-dependent non-heme dioxygenase that plays a key role in catalyzing the conversion of 4-HPP to homogentisate (HGA) in the liver [127]

In addition, both MT-I and MT-II are legally available as reference materials for research

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