doi:10.1210/en.2003-0723
The incremental GLP-1 (GLP-1) levels were calculated by subtracting the fasting GLP-1 level from the GLP-1 levels at 30 and 120 min
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These imbalances influence the expression of lipogenic genes, blood ethanol levels, and bile acid composition, thereby playing a pivotal role in the progression of hepatic steatosis [72,73,74,75,76,77,78]
Known side effects (class effects similar to other GLP-1 medications) Gastrointestinal issues (very common): Nausea: 38-43% of participants vs 11% placebo Diarrhea: 33-35% vs 13% placebo Vomiting: 20-21% vs 0% placebo Constipation: 22-25% vs 9% placebo Decreased appetite: 18-19% vs 9% placebo These are expected with incretin-based therapies and typically improve over time as your body adjusts
Obesity is significantly associated with adverse health outcomes, quality of life and increased mortality