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We added 2-deoxyglucose (2-DG) in our kinetic assay because it inhibits the early steps of glycolysis (hexokinase) [21] and subsequently downstream reactions, including the pyrophosphate pathway and the tricarboxylic acid cycle

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The mechanism through which BPC-157 influences FAK-paxillin signaling, whether through integrin-associated signaling, NO-related modulation, VEGFR2-associated events, or another upstream process, has not been definitively established across all model systems