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[6] [7] People with pre-existing retinopathy should be monitored appropriately

Clinical Focus and Substances Studied Clinical studies mainly addressed nicotine and alcohol use disorders, assessing pharmacological effects on intake, craving, abstinence, and related neuroendocrine or metabolic parameters

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In conscious swine, ipamorelin released GH with an ED 50 of about 2.3 nmol/kg, comparable to GHRP-6, while sermorelins response is constrained by somatostatin feedback

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These co-agonists have been shown to reduce glucose levels and body weight in people with overweight/obesity and type 2 diabetes, with nausea and vomiting the most frequently detected side effects (reviewed in [80, 81])