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Basic pharmacokinetic parameters including absorption, distribution, metabolism, and excretion characteristics in human subjects would inform rational dosing strategies and identify potential sources of pharmacokinetic variability affecting individual response

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Zhang L, Guo L, Wang L, Jiang X (2022b) The efficacy and safety of tofacitinib, peficitinib, solcitinib, baricitinib, abrocitinib and deucravacitinib in plaque psoriasisa network meta-analysis

The underlying biology is fundamentally different