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The mechanism involves multiple pathways working simultaneously
The role of novel antidiabetic drugs in diabetic HFpEF Emerging studies indicated that the novel antidiabetic drugs, including SGLT2i, GLP-1 RA and DPP4i, provided the cardiovascular benefits in diabetic HFpEF patients [45,46,47,48,49]
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Current evidence does not contraindicate tirzepatide in patients with asymptomatic gallstones, but the risk of those stones becoming symptomatic may increase
It has been used in other health conditions, such as high blood pressure or diabetes, for many years
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