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Significant weight reduction can lead to decreased skin elasticity, increased skin laxity, dryness, and subjective changes in skin texture
They also provide minimal nutrition when your appetite is already reduced
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Pathogenesis Cystic enlargement of perisinusoidal stellate cells (Ito cells) particularly observed in aging rats
Measurable weight loss typically begins by week three to four, with the most significant changes occurring after reaching therapeutic dose levels around weeks nine to twelve
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