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This effect typically peaks during the first week of use and diminishes substantially by week two or three

doi: 10.1097/HJH.0000000000001825 7 MallamaciFTripepiGD'ArrigoGBorrelliSGarofaloCStanzioneGet al

What is the evidence behind the evidence-base

35 So, we question whether our findings could explain, at least in part, implantation failure in women with endometriosis and repeated implantation failure after IVF and embryo transfer, which needs further investigation