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Clinical trials have utilized doses ranging from 1 mg per day up to 30 mg per day in divided doses for various administration routes, demonstrating safety across a wide dose spectrum

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Plant J 52 (5): 973-86

For example, while Lactobacillus kefiranofaciens is dominant at the beginning of fermentation , Leuconostoc mesenteroides may dominate at the end (111)

In general, to wrap up gut inflammation, glia cells, bacteria response, and CBD: A study in a lipopolysaccharide-induced model suggested that CBD, which is known to act as GPR55 antagonist [46], inhibits GI inflammation by controlling the inflammatory response and the activation of enteric glial cells

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