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(2) There does not appear to be desensitization according to the available laboratory research
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Most people regain a significant portion of lost weight within 12 months of stopping, as the appetite-suppressing effect ends
The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person
Seven healthy subjects were dosed with each test article following a cross over study design across two study visits
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